Contact Us!
Our lab would be a great fit for students and fellows who are excited about combining engineering principles with biology to solve complex problems in human health. We’re looking for students and fellows interested in fields like biomolecular engineering, synthetic biology, chemical biology, synthetic chemistry, and who are curious about how molecular-level designs can influence cellular functions and therapeutic outcomes.
We offer multiple project opportunities, examples include:
1. Engineering bifunctional antibodies for targeted degradation of cell surface receptors and signaling modulation
2. Developing cell-type-specific drug delivery methods
3. Designing synthetic mammalian receptors and pathways that detect environmental signals and activate a user-defined transcriptional program
4. Computational analysis of human biology for synthetic protein or cellular designs
A prospective student and fellow might find our projects particularly appealing if they have goals such as:
1. Developing biomolecular engineering technologies, like bifunctional antibody engineering, conformational switches, or synthetic receptors, and interrogating their applications in real-world therapeutic settings.
2. Learning how to design and manipulate biological systems to develop new solutions for targeted cell modulation, drug delivery, immune perturbation, or controlled gene expression.
3. Constructing new tools to study cell signaling pathways and disease biology.
Dana-Farber Cancer Institute
LC-3116 (office), LC-3101 (Lab)
360 Longwood Avenue
Boston, MA 02215
phone: 617-582-9749
We are keen on building a positive, caring, and inclusive laboratory environment, and are committed to training and supporting a new generation of scientists.
Graduate students from any Harvard Medical School programs should contact Xin via email directly. Prospective graduate students should apply to one of the Ph.D. programs affiliated with Harvard Medical School.
Postdoctoral candidates are invited to send Xin a CV, contact information of three references, and a cover letter describing past research, future research interest, and motivations for applying to our lab.
Research assistant and lab technician positions are available to candidates with an undergraduate degree in biology, chemistry, engineering, or a relevant topic by the start date.
We also consider inquiries from undergraduate students interested in an undergraduate research program, thesis project, or co-op/work-study credit programs.